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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, A/PLoni Bk., Taluka -Rahata,
Dist-Ahmednagar 413736, IN
2 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, 413736 (MS), IN
3 Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, 413736 (MS), IN
Source
Research Journal of Science and Technology, Vol 1, No 2 (2009), Pagination: 63-70
Abstract
Many natural products from marine sources are endowed with promising anti cancer activity, thus representing invaluable leads in the plans for drug discovery. In this context, organic synthesis plays a decisive role in confirming (or revising) the chemical structures of the natural compounds allowing also access to suitable amounts of the target (and its analogs) for structure activity relationship (SAR) investigations. In this overview, we focus on the total and partial synthesis of anti cancer marine metabolites and their related compounds discussing the retro synthetic analysis of the strategies adopted.
Keywords
Marine, Anti Cancer Activity, Synthesis of Dictyostatin.